BDBM50326284 1-(beta-D-Glucopyranosyl)-4-methyl-3-(5-(4-fluorophenyl)-2-thienylmethyl)benzene::CHEMBL1243275

SMILES Cc1cccc(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c1Cc1ccc(s1)-c1ccc(F)cc1

InChI Key InChIKey=LQCIKRNQMUFICQ-PFKOEMKTSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50326284   

TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50326284(1-(beta-D-Glucopyranosyl)-4-methyl-3-(5-(4-fluorop...)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside uptake after 120 mins by liquid scint...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 2, facilitated glucose transporter member 1(Rattus norvegicus)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50326284(1-(beta-D-Glucopyranosyl)-4-methyl-3-(5-(4-fluorop...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of GLUT1-mediated [3H]2-deoxy-glucose uptake in rat L6 cells after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50326284(1-(beta-D-Glucopyranosyl)-4-methyl-3-(5-(4-fluorop...)
Affinity DataIC50:  910nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside uptake after 120 mins by liquid scint...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed