BDBM50326985 3,3'-((2Z,2'Z)-4,4'-(3,4-dimethoxyphenethylazanediyl)bis(but-2-ene-4,1-diyl))bis(7,8-dimethoxy-1H-benzo[d]azepin-2(3H)-one)::CHEMBL1253477

SMILES COc1ccc(CCN(C\C=C/CN2C=Cc3cc(OC)c(OC)cc3CC2=O)C\C=C/CN2C=Cc3cc(OC)c(OC)cc3CC2=O)cc1OC

InChI Key InChIKey=HYAMGVKMAKVYBM-XOHWUJONSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50326985   

TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2(Mus musculus)
Laboratory Of Design, Synthesis, And Study Of Biologically Active Heterocycles (Heterobiolab)

Curated by ChEMBL
LigandPNGBDBM50326985(3,3'-((2Z,2'Z)-4,4'-(3,4-dimethoxyphenethylazanedi...)
Affinity DataEC50:  1.47E+5nMAssay Description:Blockade of mouse HCN2 expressed in HEK293 cells at -120 f-current amplitude by patch-clamp electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4(Homo sapiens (Human))
Laboratory Of Design, Synthesis, And Study Of Biologically Active Heterocycles (Heterobiolab)

Curated by ChEMBL
LigandPNGBDBM50326985(3,3'-((2Z,2'Z)-4,4'-(3,4-dimethoxyphenethylazanedi...)
Affinity DataEC50:  7.07E+4nMAssay Description:Blockade of human HCN4 expressed in HEK293 cells at -120 f-current amplitude by patch-clamp electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1(Mus musculus)
Laboratory Of Design, Synthesis, And Study Of Biologically Active Heterocycles (Heterobiolab)

Curated by ChEMBL
LigandPNGBDBM50326985(3,3'-((2Z,2'Z)-4,4'-(3,4-dimethoxyphenethylazanedi...)
Affinity DataEC50:  1.07E+5nMAssay Description:Blockade of mouse HCN1 expressed in HEK293 cells at -120 f-current amplitude by patch-clamp electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed