BDBM50327082 1-{2-Chloro-4-[(5-methyl-5H-pyrrolo[3,2-d]pyrimidin-4-yl)oxy]phenyl}-3-{3-[(4-methylpiperazin-1-yl)methyl]-5-(trifluoromethyl)phenyl}urea::CHEMBL1255097

SMILES CN1CCN(Cc2cc(NC(=O)Nc3ccc(Oc4ncnc5ccn(C)c45)cc3Cl)cc(c2)C(F)(F)F)CC1

InChI Key InChIKey=ATQDMZRXTGWPPT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50327082   

TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50327082(1-{2-Chloro-4-[(5-methyl-5H-pyrrolo[3,2-d]pyrimidi...)
Affinity DataIC50:  390nMAssay Description:Inhibition of His-tagged human FGFR1 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50327082(1-{2-Chloro-4-[(5-methyl-5H-pyrrolo[3,2-d]pyrimidi...)
Affinity DataIC50:  11nMAssay Description:Inhibition of His-tagged human VEGFR2 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed