BDBM50327092 1-(2-Chloro-4-{[5-(2-methoxyethyl)-5H-pyrrolo[3,2-d]pyr imidin-4-yl]oxy}phenyl)-3-[3-(trifluoromethyl)phenyl]urea::CHEMBL1253838

SMILES COCCn1ccc2ncnc(Oc3ccc(NC(=O)Nc4cccc(c4)C(F)(F)F)c(Cl)c3)c12

InChI Key InChIKey=AAPMNKHOEMXGDK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50327092   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50327092(1-(2-Chloro-4-{[5-(2-methoxyethyl)-5H-pyrrolo[3,2-...)
Affinity DataIC50:  9nMAssay Description:Inhibition of His-tagged human VEGFR2 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50327092(1-(2-Chloro-4-{[5-(2-methoxyethyl)-5H-pyrrolo[3,2-...)
Affinity DataIC50:  2.70E+4nMAssay Description:Inhibition of His-tagged human FGFR1 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed