BDBM50327097 1-[2-Chloro-4-({5-[2-(2-hydroxyethoxy)ethyl]-5H-pyrrolo [3,2-d]pyrimidin-4-yl}oxy)phenyl]-3-[3-(trifluoromethyl)phenyl]urea::CHEMBL1253837

SMILES OCCOCCn1ccc2ncnc(Oc3ccc(NC(=O)Nc4cccc(c4)C(F)(F)F)c(Cl)c3)c12

InChI Key InChIKey=HZMLMSFEXUJVAY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50327097   

TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50327097(1-[2-Chloro-4-({5-[2-(2-hydroxyethoxy)ethyl]-5H-py...)
Affinity DataIC50:  6.50E+3nMAssay Description:Inhibition of His-tagged human FGFR1 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50327097(1-[2-Chloro-4-({5-[2-(2-hydroxyethoxy)ethyl]-5H-py...)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of His-tagged human VEGFR2 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed