BDBM50327187 1-{5-tert-Butyl-2-[3-(1,1,3-trioxo-1lambda*6*-[1,2,5]thiadiazolidin-2-ylmethyl)-phenyl]-2H-pyrazol-3-yl}-3-(4-chloro-phenyl)-urea::1-{5-tert-Butyl-2-[3-(1,1,3-trioxo-1lambda-6-[1,2,5]thiadiazolidin-2-ylmethyl)-phenyl]-2H-pyrazol-3-yl}-3-(4-chloro-phenyl)-urea::CHEMBL1257218

SMILES CC(C)(C)c1cc(NC(=O)Nc2ccc(Cl)cc2)n(n1)-c1cccc(CN2C(O)=CNS2(=O)=O)c1

InChI Key InChIKey=PRDFENXCUNQHNA-UHFFFAOYSA-N

Data  1 KI  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50327187   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50327187(1-{5-tert-Butyl-2-[3-(1,1,3-trioxo-1lambda*6*-[1,2...)
Affinity DataKi:  99nMAssay Description:Binding affinity to full-length GST-tagged p38alpha after 2.5 hrs by TR-FRET competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50327187(1-{5-tert-Butyl-2-[3-(1,1,3-trioxo-1lambda*6*-[1,2...)
Affinity DataIC50:  57nMAssay Description:Inhibition of p38alpha by fluoroprobe binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50327187(1-{5-tert-Butyl-2-[3-(1,1,3-trioxo-1lambda*6*-[1,2...)
Affinity DataKd:  564nMAssay Description:Binding affinity to full-length GST-tagged p38alpha by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed