BDBM503273 (2R)-N-[2-(1-benzylpiperidin-4-yl)ethyl]-4-(4-cyano-3-fluoro-5- methoxyphenyl)-2-methylpiperazine-1-carboxamide::US11033539, Cpd. No. 22-32

SMILES COc1cc(cc(F)c1C#N)N1CCN([C@H](C)C1)C(=O)NCCC1CCN(Cc2ccccc2)CC1

InChI Key InChIKey=MONFTSPGJAUKAQ-OAQYLSRUSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 503273   

TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Neurocrine Biosciences

US Patent
LigandPNGBDBM503273((2R)-N-[2-(1-benzylpiperidin-4-yl)ethyl]-4-(4-cyan...)
Affinity DataKi: <10nMAssay Description:Binding affinity (Ki) of compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M1, M2, M3, M4 and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Neurocrine Biosciences

US Patent
LigandPNGBDBM503273((2R)-N-[2-(1-benzylpiperidin-4-yl)ethyl]-4-(4-cyan...)
Affinity DataKi: >100nMAssay Description:Binding affinity (Ki) of compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M1, M2, M3, M4 and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M5(Homo sapiens (Human))
Neurocrine Biosciences

US Patent
LigandPNGBDBM503273((2R)-N-[2-(1-benzylpiperidin-4-yl)ethyl]-4-(4-cyan...)
Affinity DataKi:  550nMAssay Description:Binding affinity (Ki) of compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M1, M2, M3, M4 and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Neurocrine Biosciences

US Patent
LigandPNGBDBM503273((2R)-N-[2-(1-benzylpiperidin-4-yl)ethyl]-4-(4-cyan...)
Affinity DataKi:  550nMAssay Description:Binding affinity (Ki) of compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M1, M2, M3, M4 and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Neurocrine Biosciences

US Patent
LigandPNGBDBM503273((2R)-N-[2-(1-benzylpiperidin-4-yl)ethyl]-4-(4-cyan...)
Affinity DataKi:  550nMAssay Description:Binding affinity (Ki) of compounds was measured by inhibition of radioligand binding to membranes from CHO cells expressing human M1, M2, M3, M4 and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent