BDBM50327523 2-(4-bromophenyl)-N-((7-methoxy-2-(thiophen-2-yl)quinolin-3-yl)methyl)ethanamine::CHEMBL1258530

SMILES COc1ccc2cc(CNCCc3ccc(Br)cc3)c(nc2c1)-c1cccs1

InChI Key InChIKey=DFMVHPGXMMWCLQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50327523   

TargetG-protein coupled bile acid receptor 1(Mus musculus)
Kalypsys

Curated by ChEMBL
LigandPNGBDBM50327523(2-(4-bromophenyl)-N-((7-methoxy-2-(thiophen-2-yl)q...)
Affinity DataIC50:  4.60E+3nMAssay Description:Agonist activity at mouse TGR5 receptor expressed in HEK293 cells assessed as intracellular cAMP levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Kalypsys

Curated by ChEMBL
LigandPNGBDBM50327523(2-(4-bromophenyl)-N-((7-methoxy-2-(thiophen-2-yl)q...)
Affinity DataIC50:  580nMAssay Description:Agonist activity at human TGR5 receptor expressed in HEK293 cells assessed as intracellular cAMP levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed