BDBM50327573 5-(4-(4-(naphthalen-1-yl)piperazin-1-yl)butoxy)isoindoline::CHEMBL1258425

SMILES C(CCN1CCN(CC1)c1cccc2ccccc12)COc1ccc2CNCc2c1

InChI Key InChIKey=JKWVQRPLWQNRNL-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50327573   

Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327573(5-(4-(4-(naphthalen-1-yl)piperazin-1-yl)butoxy)iso...)
Affinity DataKi:  0.204nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327573(5-(4-(4-(naphthalen-1-yl)piperazin-1-yl)butoxy)iso...)
Affinity DataKi:  5.07nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327573(5-(4-(4-(naphthalen-1-yl)piperazin-1-yl)butoxy)iso...)
Affinity DataKi:  40.7nMAssay Description:Displacement of [3H]-Spiperone from human dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327573(5-(4-(4-(naphthalen-1-yl)piperazin-1-yl)butoxy)iso...)
Affinity DataKi:  1.56E+3nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed