BDBM50327588 5-(3-(4-(naphthalen-1-yl)piperazin-1-yl)propoxy)isoindoline::CHEMBL1258312

SMILES C(COc1ccc2CNCc2c1)CN1CCN(CC1)c1cccc2ccccc12

InChI Key InChIKey=FSOQNRYVHQRTNP-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50327588   

Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327588(5-(3-(4-(naphthalen-1-yl)piperazin-1-yl)propoxy)is...)
Affinity DataKi:  0.149nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327588(5-(3-(4-(naphthalen-1-yl)piperazin-1-yl)propoxy)is...)
Affinity DataKi:  1.76nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327588(5-(3-(4-(naphthalen-1-yl)piperazin-1-yl)propoxy)is...)
Affinity DataKi:  34nMAssay Description:Displacement of [3H]-Spiperone from human dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327588(5-(3-(4-(naphthalen-1-yl)piperazin-1-yl)propoxy)is...)
Affinity DataKi:  779nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed