BDBM50327626 6-(4-(4-(5,6,7,8-tetrahydronaphthalen-1-yl)piperazin-1-yl)butoxy)isoindolin-1-one::CHEMBL1257614

SMILES O=C1NCc2ccc(OCCCCN3CCN(CC3)c3cccc4CCCCc34)cc12

InChI Key InChIKey=ONXAINPGJUQBMC-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50327626   

TargetD(2) dopamine receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327626(6-(4-(4-(5,6,7,8-tetrahydronaphthalen-1-yl)piperaz...)
Affinity DataKi:  1.54nMAssay Description:Displacement of [3H]-Spiperone from human dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327626(6-(4-(4-(5,6,7,8-tetrahydronaphthalen-1-yl)piperaz...)
Affinity DataKi:  1.92nMAssay Description:Binding affinity to human 5HT1A receptor expressed in HeLa cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327626(6-(4-(4-(5,6,7,8-tetrahydronaphthalen-1-yl)piperaz...)
Affinity DataKi:  3.35nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed