BDBM50327812 1-(Naphthalen-2-yl)-3-(1-propionylpiperidin-4-yl)urea::CHEMBL1257516::US9296693, 8

SMILES CCC(=O)N1CCC(CC1)NC(=O)Nc1ccc2ccccc2c1

InChI Key InChIKey=TZULJTFMCGRCBK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50327812   

TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
The Regents Of The University Of California

US Patent
LigandPNGBDBM50327812(1-(Naphthalen-2-yl)-3-(1-propionylpiperidin-4-yl)u...)
Affinity DataIC50:  3nMpH: 7.0Assay Description:IC50 values were determined using a sensitive fluorescent based assay (Anal. Biochem. 2005, 343, 66-75). Cyano(2-methoxynaphthalen-6-yl)methyl trans-...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
The Regents Of The University Of California

US Patent
LigandPNGBDBM50327812(1-(Naphthalen-2-yl)-3-(1-propionylpiperidin-4-yl)u...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Mus musculus (Mouse))
Department Of Entomology And University Of California Davis Cancer Center

Curated by ChEMBL
LigandPNGBDBM50327812(1-(Naphthalen-2-yl)-3-(1-propionylpiperidin-4-yl)u...)
Affinity DataIC50:  4.20nMAssay Description:Inhibition of mouse recombinant soluble epoxide hydrolase by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Mus musculus (Mouse))
Department Of Entomology And University Of California Davis Cancer Center

Curated by ChEMBL
LigandPNGBDBM50327812(1-(Naphthalen-2-yl)-3-(1-propionylpiperidin-4-yl)u...)
Affinity DataIC50:  4.20nMpH: 7.0Assay Description:IC50 values were determined using a sensitive fluorescent based assay (Anal. Biochem. 2005, 343, 66-75). Cyano(2-methoxynaphthalen-6-yl)methyl trans-...More data for this Ligand-Target Pair
In DepthDetails US Patent