BDBM50327963 CHEMBL1257888::cis-N-(4-(4-amino-1-(4-(4-methylpiperazin-1-yl)cyclohexyl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl)phenyl)-7-chlorobenzo[d]oxazol-2-amine

SMILES CN1CCN(CC1)[C@H]1CC[C@H](CC1)n1nc(-c2ccc(Nc3nc4cccc(Cl)c4o3)cc2)c2c(N)ncnc12

InChI Key InChIKey=DLQXAWIVHRHOQT-OYRHEFFESA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50327963   

TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50327963(CHEMBL1257888 | cis-N-(4-(4-amino-1-(4-(4-methylpi...)
Affinity DataIC50:  77nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50327963(CHEMBL1257888 | cis-N-(4-(4-amino-1-(4-(4-methylpi...)
Affinity DataIC50:  78nMAssay Description:Inhibition of Homo sapiens (human) recombinant C-terminal GST-tagged IGF1R expressed in baculovirus infected Sf21 cells by homogeneous time-resolved ...More data for this Ligand-Target Pair
In DepthDetails Article
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50327963(CHEMBL1257888 | cis-N-(4-(4-amino-1-(4-(4-methylpi...)
Affinity DataIC50:  77nMAssay Description:Inhibition of Homo sapiens (human) recombinant C-terminal GST-tagged IGF1R expressed in baculovirus infected Sf21 cells by homogeneous time-resolved ...More data for this Ligand-Target Pair
In DepthDetails Article
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50327963(CHEMBL1257888 | cis-N-(4-(4-amino-1-(4-(4-methylpi...)
Affinity DataIC50:  200nMAssay Description:Inhibition of ErbB2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed