BDBM50328041 CHEMBL1258686::N-((2S,3R)-4-(1-(3-tert-butylisoxazol-5-yl)cyclohexylamino)-1-(3,5-difluorophenyl)-3-hydroxybutan-2-yl)acetamide

SMILES CC(=O)N[C@@H](Cc1cc(F)cc(F)c1)[C@H](O)CNC1(CCCCC1)c1cc(no1)C(C)(C)C

InChI Key InChIKey=PQUNMNGRCLHJOJ-LEWJYISDSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50328041   

TargetCathepsin D(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328041(CHEMBL1258686 | N-((2S,3R)-4-(1-(3-tert-butylisoxa...)
Affinity DataIC50:  263nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328041(CHEMBL1258686 | N-((2S,3R)-4-(1-(3-tert-butylisoxa...)
Affinity DataIC50:  4.46E+3nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed