BDBM50328043 CHEMBL1258802::N-((2S,3R)-4-(1-(5-tert-butyloxazol-2-yl)cyclohexylamino)-1-(3,5-difluorophenyl)-3-hydroxybutan-2-yl)acetamide

SMILES CC(=O)N[C@@H](Cc1cc(F)cc(F)c1)[C@H](O)CNC1(CCCCC1)c1ncc(o1)C(C)(C)C

InChI Key InChIKey=GRQMATBKELVAAS-LEWJYISDSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50328043   

TargetCathepsin D(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328043(CHEMBL1258802 | N-((2S,3R)-4-(1-(5-tert-butyloxazo...)
Affinity DataIC50:  310nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328043(CHEMBL1258802 | N-((2S,3R)-4-(1-(5-tert-butyloxazo...)
Affinity DataIC50:  1.58E+3nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed