BDBM50328199 1-ethyl-N-(4-(trifluoromethoxy)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine::CHEMBL1258011::US9670214, TABLE 10.2

SMILES CCn1ncc2c(Nc3ccc(OC(F)(F)F)cc3)ncnc12

InChI Key InChIKey=SAXPEWWZWJCVAP-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50328199   

TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50328199(1-ethyl-N-(4-(trifluoromethoxy)phenyl)-1H-pyrazolo...)
Affinity DataEC50:  300nMAssay Description:Inhibition of Bcr-Abl in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed