BDBM50328502 CHEMBL1259158::N-((11-(4-Methylpiperazin-1-yl)-10,11-dihydrodibenzo[b,f]thiepin-2-yl)methyl)pivalamide

SMILES CN1CCN(CC1)C1Cc2ccccc2Sc2ccc(CNC(=O)C(C)(C)C)cc12

InChI Key InChIKey=CKLAPTDGXNWXQT-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50328502   

TargetAlpha-1D adrenergic receptor(Rattus norvegicus (Rat))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50328502(CHEMBL1259158 | N-((11-(4-Methylpiperazin-1-yl)-10...)
Affinity DataKi:  0.370nMAssay Description:Displacement of [3H]prozosin from rat cloned alpha1d receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(C.H.O.)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50328502(CHEMBL1259158 | N-((11-(4-Methylpiperazin-1-yl)-10...)
Affinity DataKi:  0.520nMAssay Description:Displacement of [3H]prozosin from hamster cloned alpha1b receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(CALF)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50328502(CHEMBL1259158 | N-((11-(4-Methylpiperazin-1-yl)-10...)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]prozosin from bovine cloned alpha1a receptor expressed in BHK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50328502(CHEMBL1259158 | N-((11-(4-Methylpiperazin-1-yl)-10...)
Affinity DataKi:  6.10nMAssay Description:Displacement of [3H]prozosin from human cloned dopamine D2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed