BDBM50328697 (R)-5-guanidino-N-(2-((S)-5-guanidino-1-oxo-1-(thiazol-2-yl)pentan-2-ylamino)-2-oxoethyl)-2-(phenylmethylsulfonamido)pentanamide::CHEMBL414002
SMILES [#7]\[#6](-[#7])=[#7]\[#6]-[#6]-[#6]-[#6@H](-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]S(=O)(=O)[#6]-c1ccccc1)-[#6](=O)-c1nccs1
InChI Key InChIKey=BZGZTAKGLPGMAV-ZWKOTPCHSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50328697
TargetCoagulation factor X(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataKi: 0.0140nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of human factor 12a using Z-D-Arg-Gly-Arg-pNA as substrate preincubated for 5 mins followed by substrate addition by absorbance methodMore data for this Ligand-Target Pair
TargetPlasma kallikrein(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of kallikreinMore data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 0.130nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of factor 12aMore data for this Ligand-Target Pair