BDBM50328817 CHEMBL1270460::N-(3-Fluorophenethyl)-2-((3R,4R)-4-((6-iminopiperidin-2-yl)methyl)pyrrolidin-3-yloxy)ethanamine
SMILES NC1=NC(C[C@@H]2CNC[C@@H]2OCCNCCc2cccc(F)c2)CCC1
InChI Key InChIKey=HZHJCKDWMOAWJH-WDOSNPKHSA-N
Data 4 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50328817
Affinity DataKi: 110nMAssay Description:Inhibition of rat nNOS expressed in Escherichia coli assessed as inhibition of nitric oxide formation by hemoglobin capture assayMore data for this Ligand-Target Pair
Affinity DataKi: 490nMAssay Description:Inhibition of human nNOS expressed in Escherichia coli assessed as inhibition of nitric oxide formation by hemoglobin capture assayMore data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Northwestern University
Curated by ChEMBL
Northwestern University
Curated by ChEMBL
Affinity DataKi: 2.18E+4nMAssay Description:Inhibition of mouse iNOS expressed in Escherichia coli assessed as inhibition of nitric oxide formation by hemoglobin capture assayMore data for this Ligand-Target Pair
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
Northwestern University
Curated by ChEMBL
Northwestern University
Curated by ChEMBL
Affinity DataKi: 5.80E+4nMAssay Description:Inhibition of bovine eNOS expressed in Escherichia coli assessed as inhibition of nitric oxide formation by hemoglobin capture assayMore data for this Ligand-Target Pair