BDBM50329072 (3-(4-((1H-indazol-4-yl)(methyl)amino)pyrimidin-2-ylamino)phenyl)methanol::CHEMBL1269964

SMILES CN(c1ccnc(Nc2cccc(CO)c2)n1)c1cccc2[nH]ncc12

InChI Key InChIKey=KFNNEFIVNZLLBN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50329072   

TargetEphrin type-B receptor 4(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50329072((3-(4-((1H-indazol-4-yl)(methyl)amino)pyrimidin-2-...)
Affinity DataIC50:  232nMAssay Description:Inhibition of EphB4 autophosphorylation expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50329072((3-(4-((1H-indazol-4-yl)(methyl)amino)pyrimidin-2-...)
Affinity DataIC50:  21nMAssay Description:Inhibition of EphB4 by acoustic dispensing assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed