BDBM50329499 CHEMBL1270331::N-(6-benzyl-2-(phenethylamino)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-yl)-3-chloro-2-methylbenzenesulfonamide

SMILES Cc1c(Cl)cccc1S(=O)(=O)Nc1nc(NCCc2ccccc2)nc2CCN(Cc3ccccc3)Cc12

InChI Key InChIKey=LGUUETDTMQTHML-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50329499   

TargetMyosin light chain kinase, smooth muscle(Homo sapiens (Human))
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50329499(CHEMBL1270331 | N-(6-benzyl-2-(phenethylamino)-5,6...)
Affinity DataIC50:  3.60E+4nMAssay Description:Inhibition of MLCKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcium/calmodulin-dependent protein kinase type IV(Homo sapiens (Human))
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50329499(CHEMBL1270331 | N-(6-benzyl-2-(phenethylamino)-5,6...)
Affinity DataIC50: >6.00E+4nMAssay Description:Inhibition of CAMK4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50329499(CHEMBL1270331 | N-(6-benzyl-2-(phenethylamino)-5,6...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of AKT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50329499(CHEMBL1270331 | N-(6-benzyl-2-(phenethylamino)-5,6...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed