BDBM50329707 (S)-3-(4-(3-(4-((S)-2-hydroxy-3,3-dimethylbutoxy)-3-methylphenyl)pentan-3-yl)-2-methylphenoxy)propane-1,2-diol::CHEMBL403885

SMILES CCC(CC)(c1ccc(OC[C@@H](O)CO)c(C)c1)c1ccc(OC[C@@H](O)C(C)(C)C)c(C)c1

InChI Key InChIKey=AIKLCYAFOOBGEV-JYFHCDHNSA-N

Data  2 KI  1 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50329707   

TargetVitamin D3 receptor(Homo sapiens (Human))
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50329707((S)-3-(4-(3-(4-((S)-2-hydroxy-3,3-dimethylbutoxy)-...)
Affinity DataKi:  11nMAssay Description:Binding affinity to VDR receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50329707((S)-3-(4-(3-(4-((S)-2-hydroxy-3,3-dimethylbutoxy)-...)
Affinity DataKi:  1.10E+3nMAssay Description:Binding affinity to androgen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50329707((S)-3-(4-(3-(4-((S)-2-hydroxy-3,3-dimethylbutoxy)-...)
Affinity DataEC50:  9.90nMAssay Description:Effect on VDR transcriptional activity in human osteosarcoma cells in presence of 5% fetal calf serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Mus musculus)
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50329707((S)-3-(4-(3-(4-((S)-2-hydroxy-3,3-dimethylbutoxy)-...)
Affinity DataIC50:  13nMAssay Description:Antiandrogen activity against androgen receptor in androgen-dependent mouse SC3 cells assessed as inhibition of testosterone-induced cell proliferati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50329707((S)-3-(4-(3-(4-((S)-2-hydroxy-3,3-dimethylbutoxy)-...)
Affinity DataEC50:  1.66nMAssay Description:Effect on VDR transcriptional activity in human osteosarcoma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50329707((S)-3-(4-(3-(4-((S)-2-hydroxy-3,3-dimethylbutoxy)-...)
Affinity DataEC50:  23nMAssay Description:Vitamin-D activity at VDR receptor in human HL60 cells assessed as induction of cell differentiation by NBT reduction assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50329707((S)-3-(4-(3-(4-((S)-2-hydroxy-3,3-dimethylbutoxy)-...)
Affinity DataEC50:  21.1nMAssay Description:Effect on VDR transcriptional activity in human Caco-2 cells in presence of 5% fetal calf serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed