BDBM50330422 CHEMBL4176772

SMILES NCc1cccc(Nc2n[nH]c3ncnc(Nc4cccc(O)c4)c23)c1

InChI Key InChIKey=OUMZUIUUJCKLOT-UHFFFAOYSA-N

Data  1 IC50  1 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50330422   

TargetComplement factor D(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50330422(CHEMBL4176772)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of recombinant complement factor D catalytic domain (unknown origin) using Z-Lys-thiobenzyl as substrate pretreated for 1 hr followed by s...More data for this Ligand-Target Pair
TargetComplement factor D(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50330422(CHEMBL4176772)
Affinity DataKd:  5.00E+4nMAssay Description:Displacement of 19F[(S)-methyl 2-((2-(3-(trifluoromethoxy)phenylcarbamoyl)pyrrolidine-1-carboxamido)methyl)benzoate] from complement factor D (unknow...More data for this Ligand-Target Pair