BDBM50330623 3-Benzyl-1-methyl-9-thiophen-3-yl-pyrazolo[1',5':1,6]pyrimido[4,5-d]pyridazin-4(3H)-one::CHEMBL1278102

SMILES Cc1nn(Cc2ccccc2)c(=O)c2ncn3nc(cc3c12)-c1ccsc1

InChI Key InChIKey=PNXKNLVMBBJLFQ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50330623   

TargetAdenosine receptor A1(Homo sapiens (Human))
Dipartimento Di Scienze Farmaceutiche

Curated by ChEMBL
LigandPNGBDBM50330623(3-Benzyl-1-methyl-9-thiophen-3-yl-pyrazolo[1',5':1...)
Affinity DataKi:  85nMAssay Description:Binding affinity to human adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Dipartimento Di Scienze Farmaceutiche

Curated by ChEMBL
LigandPNGBDBM50330623(3-Benzyl-1-methyl-9-thiophen-3-yl-pyrazolo[1',5':1...)
Affinity DataKi:  4.65E+3nMAssay Description:Displacement of [3H]DPCPX from human adenosine A2b receptor expressed in HEK293 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Dipartimento Di Scienze Farmaceutiche

Curated by ChEMBL
LigandPNGBDBM50330623(3-Benzyl-1-methyl-9-thiophen-3-yl-pyrazolo[1',5':1...)
Affinity DataKi:  7.37E+3nMAssay Description:Binding affinity to human adenosine A2a receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed