BDBM50331011 1-(1-(9-methyl-9-azabicyclo[3.3.1]nonan-3-yl)indolin-2-one::CHEMBL1276200
SMILES CN1C2CCCC1CC(C2)N1C(=O)Cc2ccccc12
InChI Key InChIKey=GIDZCNCCCWFCIN-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50331011
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Rattus norvegicus (Rat))
Sri International
Curated by ChEMBL
Sri International
Curated by ChEMBL
Affinity DataKi: 508nMAssay Description:Displacement of [3H]epibatidine from rat alpha3beta4 nAChR expressed in HEK292 cells after 3 hrsMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Sri International
Curated by ChEMBL
Sri International
Curated by ChEMBL
Affinity DataKi: 1.00E+5nMAssay Description:Displacement of [3H]epibatidine from rat alpha4beta2 nAChR expressed in HEK292 cells after 3 hrsMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Sri International
Curated by ChEMBL
Sri International
Curated by ChEMBL
Affinity DataKi: 1.00E+5nMAssay Description:Displacement of [3H]epibatidine from alpha7 nAChR in rat brain membranes after 2 hrsMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Rattus norvegicus (Rat))
Sri International
Curated by ChEMBL
Sri International
Curated by ChEMBL
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at rat alpha3beta4 nAChR expressed in HEK292 cells assessed as increase of calcium influx by FLIPR assayMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Rattus norvegicus (Rat))
Sri International
Curated by ChEMBL
Sri International
Curated by ChEMBL
Affinity DataIC50: 1.02E+4nMAssay Description:Antagonist activity at rat alpha3beta4 nAChR expressed in HEK292 cells assessed as inhibition of epibatidine-induced calcium influx by FLIPR assayMore data for this Ligand-Target Pair