BDBM50331037 (S)-2-((S)-1-((S)-2-((5R,8S,11R)-11-amino-8-(4-hydroxybenzyl)-7,10-dioxo-1,2-dithia-6,9-diazacyclotridecane-5-carboxamido)-3-(1H-imidazol-5-yl)propanoyl)pyrrolidine-2-carboxamido)-3-phenylpropanoic acid::CHEMBL1275684

SMILES N[C@@H]1CCSSCC[C@@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(O)=O

InChI Key InChIKey=VONFJXUWECQUIR-CJKOIZGMSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50331037   

TargetLeucyl-cystinyl aminopeptidase(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50331037((S)-2-((S)-1-((S)-2-((5R,8S,11R)-11-amino-8-(4-hyd...)
Affinity DataKi:  196nMAssay Description:Displacement of [3H]AL-11 from human IRAP expressed in CHO-K1 cells after 30 mins by liquid scintillation counting in presence of 30 mM EDTA/600 uM 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucyl-cystinyl aminopeptidase(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50331037((S)-2-((S)-1-((S)-2-((5R,8S,11R)-11-amino-8-(4-hyd...)
Affinity DataKi:  303nMAssay Description:Inhibition of catalytic activity of human recombinant IRAP expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucyl-cystinyl aminopeptidase(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50331037((S)-2-((S)-1-((S)-2-((5R,8S,11R)-11-amino-8-(4-hyd...)
Affinity DataKi:  1.49E+3nMAssay Description:Displacement of [3H]AL-11 from human IRAP expressed in CHO-K1 cells after 30 mins by liquid scintillation counting in absence of 30 mM EDTA/600 uM 1,...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50331037((S)-2-((S)-1-((S)-2-((5R,8S,11R)-11-amino-8-(4-hyd...)
Affinity DataKi:  5.97E+3nMAssay Description:Inhibition of catalytic activity of human recombinant aminopeptidase N expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed