BDBM50331039 2-(2-(((5R,8S,11S)-11-amino-8-(4-hydroxybenzyl)-7,10-dioxo-1,2-dithia-6,9-diazacyclotridecane-5-carboxamido)methyl)phenyl)acetic acid::CHEMBL1277530

SMILES N[C@H]1CCSSCC[C@@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(=O)NCc1ccccc1CC(O)=O

InChI Key InChIKey=BYRWDJKBMMPGOL-BDTNDASRSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50331039   

TargetLeucyl-cystinyl aminopeptidase(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50331039(2-(2-(((5R,8S,11S)-11-amino-8-(4-hydroxybenzyl)-7,...)
Affinity DataKi:  282nMAssay Description:Inhibition of catalytic activity of human recombinant IRAP expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucyl-cystinyl aminopeptidase(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50331039(2-(2-(((5R,8S,11S)-11-amino-8-(4-hydroxybenzyl)-7,...)
Affinity DataKi:  1.19E+3nMAssay Description:Displacement of [3H]AL-11 from human IRAP expressed in CHO-K1 cells after 30 mins by liquid scintillation counting in presence of 30 mM EDTA/600 uM 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50331039(2-(2-(((5R,8S,11S)-11-amino-8-(4-hydroxybenzyl)-7,...)
Affinity DataKi:  3.59E+3nMAssay Description:Inhibition of catalytic activity of human recombinant aminopeptidase N expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeucyl-cystinyl aminopeptidase(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50331039(2-(2-(((5R,8S,11S)-11-amino-8-(4-hydroxybenzyl)-7,...)
Affinity DataKi:  1.02E+4nMAssay Description:Displacement of [3H]AL-11 from human IRAP expressed in CHO-K1 cells after 30 mins by liquid scintillation counting in absence of 30 mM EDTA/600 uM 1,...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed