BDBM503316 2-(4-Amino-4-methyl-piperidin-1- yl)-6-chloro-5-(2,3-dichloro-phenyl)- pyrimidine-4-carboxylic acid amide::US11033547, Compound 16
SMILES CC1(N)CCN(CC1)c1nc(Cl)c(c(n1)C(N)=O)-c1cccc(Cl)c1Cl
InChI Key InChIKey=VZAWBEPGIGHBCI-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 503316
Affinity DataIC50: 60nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair