BDBM503316 2-(4-Amino-4-methyl-piperidin-1- yl)-6-chloro-5-(2,3-dichloro-phenyl)- pyrimidine-4-carboxylic acid amide::US11033547, Compound 16

SMILES CC1(N)CCN(CC1)c1nc(Cl)c(c(n1)C(N)=O)-c1cccc(Cl)c1Cl

InChI Key InChIKey=VZAWBEPGIGHBCI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 503316   

TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM503316(2-(4-Amino-4-methyl-piperidin-1- yl)-6-chloro-5-(2...)
Affinity DataIC50:  60nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent