BDBM50331772 (S)-N-((S)-1-cyano-2-phenylethyl)-2-((S)-1-(4'-((R)-2,2-difluoro-1-hydroxyethyl)biphenyl-4-yl)-2,2,2-trifluoroethylamino)-4-fluoro-4-methylpentanamide::CHEMBL1288527

SMILES CC(C)(F)C[C@H](N[C@@H](c1ccc(cc1)-c1ccc(cc1)[C@@H](O)C(F)F)C(F)(F)F)C(=O)N[C@@H](Cc1ccccc1)C#N

InChI Key InChIKey=KNPHXKWUIHWCRM-NFGXINMFSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50331772   

TargetCathepsin F(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50331772((S)-N-((S)-1-cyano-2-phenylethyl)-2-((S)-1-(4'-((R...)
Affinity DataIC50:  64nMAssay Description:Inhibition of human Cat F expressed in rabbit HIG82 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50331772((S)-N-((S)-1-cyano-2-phenylethyl)-2-((S)-1-(4'-((R...)
Affinity DataIC50:  48nMAssay Description:Inhibition of human Cat B in HepG2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50331772((S)-N-((S)-1-cyano-2-phenylethyl)-2-((S)-1-(4'-((R...)
Affinity DataIC50:  8nMAssay Description:Inhibition of trypanosoma cruzi CruzipainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50331772((S)-N-((S)-1-cyano-2-phenylethyl)-2-((S)-1-(4'-((R...)
Affinity DataIC50:  1.09E+3nMAssay Description:Inhibition of human Cat LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed