BDBM50331773 (S)-N-((S)-1-cyano-2-phenylethyl)-4-fluoro-4-methyl-2-((S)-2,2,2-trifluoro-1-(4'-(pyridin-4-yl)biphenyl-4-yl)ethylamino)pentanamide::CHEMBL1288528

SMILES CC(C)(F)C[C@H](N[C@@H](c1ccc(cc1)-c1ccc(cc1)-c1ccncc1)C(F)(F)F)C(=O)N[C@@H](Cc1ccccc1)C#N

InChI Key InChIKey=BTPGQECHVMXBDU-CHQNGUEUSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50331773   

TargetCathepsin F(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50331773((S)-N-((S)-1-cyano-2-phenylethyl)-4-fluoro-4-methy...)
Affinity DataIC50:  51nMAssay Description:Inhibition of human Cat F expressed in rabbit HIG82 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50331773((S)-N-((S)-1-cyano-2-phenylethyl)-4-fluoro-4-methy...)
Affinity DataIC50:  54nMAssay Description:Inhibition of human Cat B in HepG2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50331773((S)-N-((S)-1-cyano-2-phenylethyl)-4-fluoro-4-methy...)
Affinity DataIC50:  8nMAssay Description:Inhibition of trypanosoma cruzi CruzipainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50331773((S)-N-((S)-1-cyano-2-phenylethyl)-4-fluoro-4-methy...)
Affinity DataIC50:  436nMAssay Description:Inhibition of human Cat LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed