BDBM503318 2-(4-Amino-4-methyl-piperidin-1- yl)-5-(2,3-dichlorophenyl)-6-methyl- pyrimidine-4-carboxylic acid amide::US11033547, Compound 18
SMILES Cc1nc(nc(C(N)=O)c1-c1cccc(Cl)c1Cl)N1CCC(C)(N)CC1
InChI Key InChIKey=OSTNOOSXOQHKOQ-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 503318
Affinity DataIC50: 104nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair