BDBM503318 2-(4-Amino-4-methyl-piperidin-1- yl)-5-(2,3-dichlorophenyl)-6-methyl- pyrimidine-4-carboxylic acid amide::US11033547, Compound 18

SMILES Cc1nc(nc(C(N)=O)c1-c1cccc(Cl)c1Cl)N1CCC(C)(N)CC1

InChI Key InChIKey=OSTNOOSXOQHKOQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 503318   

TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM503318(2-(4-Amino-4-methyl-piperidin-1- yl)-5-(2,3-dichlo...)
Affinity DataIC50:  104nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent