BDBM50331808 (R)-9-fluoro-6-(1,1,1-trifluoro-3-methylbutan-2-ylamino)benzo[c][1,6]naphthyridin-1(2H)-one::CHEMBL1289097
SMILES CC(C)[C@@H](Nc1nc2cc[nH]c(=O)c2c2cc(F)ccc12)C(F)(F)F
InChI Key InChIKey=SDYVZQPJOBQDEW-CQSZACIVSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50331808
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck
Curated by ChEMBL
Merck
Curated by ChEMBL
Affinity DataIC50: 3.50E+3nMAssay Description:Binding affinity to human ERG expressed in HEK cells by radioligand displacement assayMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of JAK2 expressed in human Du-145 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of JAK2 in cell-free systemMore data for this Ligand-Target Pair