BDBM50331808 (R)-9-fluoro-6-(1,1,1-trifluoro-3-methylbutan-2-ylamino)benzo[c][1,6]naphthyridin-1(2H)-one::CHEMBL1289097

SMILES CC(C)[C@@H](Nc1nc2cc[nH]c(=O)c2c2cc(F)ccc12)C(F)(F)F

InChI Key InChIKey=SDYVZQPJOBQDEW-CQSZACIVSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50331808   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50331808((R)-9-fluoro-6-(1,1,1-trifluoro-3-methylbutan-2-yl...)
Affinity DataIC50:  3.50E+3nMAssay Description:Binding affinity to human ERG expressed in HEK cells by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50331808((R)-9-fluoro-6-(1,1,1-trifluoro-3-methylbutan-2-yl...)
Affinity DataIC50:  50nMAssay Description:Inhibition of JAK2 expressed in human Du-145 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50331808((R)-9-fluoro-6-(1,1,1-trifluoro-3-methylbutan-2-yl...)
Affinity DataIC50:  1nMAssay Description:Inhibition of JAK2 in cell-free systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed