BDBM50332722 CHEMBL4171835

SMILES CC(C)CC(=O)Nc1cc(cc(c1)-c1cccc(CN)c1)C(=O)N[C@H]1CCCc2ccccc12

InChI Key InChIKey=ZHDSPGRQBMRBOL-MHZLTWQESA-N

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50332722   

TargetComplement factor D(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50332722(CHEMBL4171835)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of recombinant complement factor D catalytic domain (unknown origin) using Z-Lys-thiobenzyl as substrate pretreated for 1 hr followed by s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement factor D(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50332722(CHEMBL4171835)
Affinity DataKd: <1.00E+4nMAssay Description:Displacement of 19F[(S)-methyl 2-((2-(3-(trifluoromethoxy)phenylcarbamoyl)pyrrolidine-1-carboxamido)methyl)benzoate] from complement factor D (unknow...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetComplement factor D(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50332722(CHEMBL4171835)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of complement factor D (unknown origin) by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed