BDBM50333120 CHEMBL1631581::Rustmicin

SMILES CC[C@@H]1CC(=O)[C@H](C)C(=O)[C@@](O)(CO)C\C(OC)=C\[C@@H](C)CC(=C)\C=C1/C

InChI Key InChIKey=LCMZUWGOWDQRBC-WGUQXDEUSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50333120   

TargetInositol phosphorylceramide synthase(Candida albicans)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50333120(CHEMBL1631581 | Rustmicin)
Affinity DataKi:  16nMAssay Description:Inhibition of Candida albicans ATCC 38247 inositol phosphorylceramide synthase preincubated for 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInositol phosphorylceramide synthase(Candida albicans)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50333120(CHEMBL1631581 | Rustmicin)
Affinity DataIC50:  3.80nMAssay Description:Reversible inhibition of Candida albicans inositol phosphorylceramide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInositol phosphorylceramide synthase catalytic subunit AUR1(Saccharomyces cerevisiae S288c)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50333120(CHEMBL1631581 | Rustmicin)
Affinity DataIC50:  13nMAssay Description:Inhibition of Saccharomyces cerevisiae SJ21R inositol phosphorylceramide synthase preincubated for 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInositol phosphorylceramide synthase catalytic subunit AUR1(Saccharomyces cerevisiae S288c)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50333120(CHEMBL1631581 | Rustmicin)
Affinity DataIC50:  2.72E+4nMAssay Description:Inhibition of aureobasidin A-resistant Saccharomyces cerevisiae inositol phosphorylceramide synthase preincubated for 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInositol phosphorylceramide synthase catalytic subunit AUR1(Saccharomyces cerevisiae S288c)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50333120(CHEMBL1631581 | Rustmicin)
Affinity DataIC50:  3.80nMAssay Description:Reversible inhibition of Saccharomyces cerevisiae inositol phosphorylceramide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed