BDBM50333160 9-Methyl-2-phenyl-2,6-dihydro[1,2,4]triazolo[4,3-c]quinazoline-3,5-dione::CHEMBL1644823

SMILES Cc1ccc2[nH]c(=O)n3c(nn(-c4ccccc4)c3=O)c2c1

InChI Key InChIKey=OGBTVLIUFUJHTH-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50333160   

TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Homo sapiens (Human))
Lund University

Curated by ChEMBL
LigandPNGBDBM50333160(9-Methyl-2-phenyl-2,6-dihydro[1,2,4]triazolo[4,3-c...)
Affinity DataKi:  0.430nMAssay Description:Displacement of [3H]flumazenil human recombinant alpha1beta3gamma2 GABA(A) receptor expressed in HEK293 cells after 30 mins by glass fiber filtration...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-2/beta-3/gamma-2(Homo sapiens (Human))
Lund University

Curated by ChEMBL
LigandPNGBDBM50333160(9-Methyl-2-phenyl-2,6-dihydro[1,2,4]triazolo[4,3-c...)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]flumazenil human recombinant alpha2beta3gamma2 GABA(A) receptor expressed in HEK293 cells after 30 mins by glass fiber filtration...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
Lund University

Curated by ChEMBL
LigandPNGBDBM50333160(9-Methyl-2-phenyl-2,6-dihydro[1,2,4]triazolo[4,3-c...)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]flumazenil human recombinant alpha3beta3gamma2 GABA(A) receptor expressed in HEK293 cells after 30 mins by glass fiber filtration...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed