BDBM503332 2-[(4-Amino-cyclohexyl)-methyl- amino]-5-(2,3-dichlorophenyl)-6- methyl-pyrimidine-4-carboxylic acid amide::US11033547, Compound 32

SMILES CN(C1CCC(N)CC1)c1cc(C(N)=O)c(c(C)n1)-c1cccc(Cl)c1Cl

InChI Key InChIKey=ZIBGSXLCGSPZTE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 503332   

TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM503332(2-[(4-Amino-cyclohexyl)-methyl- amino]-5-(2,3-dich...)
Affinity DataIC50:  200nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent