BDBM50333377 5-((4-aminopiperidin-1-yl)methyl)-N-p-tolylpyrrolo[1,2-f][1,2,4]triazin-4-amine::CHEMBL1645471

SMILES Cc1ccc(Nc2ncnn3ccc(CN4CCC(N)CC4)c23)cc1

InChI Key InChIKey=DNUXMLXSNBBBRZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50333377   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50333377(5-((4-aminopiperidin-1-yl)methyl)-N-p-tolylpyrrolo...)
Affinity DataIC50:  50nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50333377(5-((4-aminopiperidin-1-yl)methyl)-N-p-tolylpyrrolo...)
Affinity DataIC50:  6nMAssay Description:Inhibition of HER2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed