BDBM50333380 5-((4-aminopiperidin-1-yl)methyl)-N-phenylpyrrolo[1,2-f][1,2,4]triazin-4-amine::CHEMBL1645467

SMILES NC1CCN(Cc2ccn3ncnc(Nc4ccccc4)c23)CC1

InChI Key InChIKey=JPKXJWBKGYESKN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50333380   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50333380(5-((4-aminopiperidin-1-yl)methyl)-N-phenylpyrrolo[...)
Affinity DataIC50:  40nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50333380(5-((4-aminopiperidin-1-yl)methyl)-N-phenylpyrrolo[...)
Affinity DataIC50:  9nMAssay Description:Inhibition of HER2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed