BDBM50333384 5-((4-aminopiperidin-1-yl)methyl)-N-(3-chloro-4-methoxyphenyl)pyrrolo[1,2-f][1,2,4]triazin-4-amine::CHEMBL1645477

SMILES COc1ccc(Nc2ncnn3ccc(CN4CCC(N)CC4)c23)cc1Cl

InChI Key InChIKey=MDJCMNYFTLUIDM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50333384   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50333384(5-((4-aminopiperidin-1-yl)methyl)-N-(3-chloro-4-me...)
Affinity DataIC50:  210nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50333384(5-((4-aminopiperidin-1-yl)methyl)-N-(3-chloro-4-me...)
Affinity DataIC50:  70nMAssay Description:Inhibition of HER2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed