BDBM503345 2-(4-Amino-4-methyl-azepan-1-yl)- 5-(2,3-dichloro-phenyl)-6-methyl- pyrimidine-4-carboxylic acid amide::US11033547, Compound 45::US11696916, Compound 45
SMILES Cc1nc(nc(C(N)=O)c1-c1cccc(Cl)c1Cl)N1CCCC(C)(N)CC1
InChI Key InChIKey=NMZXLTJREWPHKA-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 503345
Affinity DataIC50: 170nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair