BDBM50334884 5-(piperidin-3-yl)-3-(prop-1-enyl)pyrazolo[1,5-a]pyrimidin-7-amine::CHEMBL1643242

SMILES C\C=C\c1cnn2c(N)cc(nc12)C1CCCNC1

InChI Key InChIKey=VXDPFMYYPUZIQV-DUXPYHPUSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50334884   

TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50334884(5-(piperidin-3-yl)-3-(prop-1-enyl)pyrazolo[1,5-a]p...)
Affinity DataIC50:  5.10E+3nMAssay Description:Inhibition of recombinant His-CHK1 expressed in baculovirus after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50334884(5-(piperidin-3-yl)-3-(prop-1-enyl)pyrazolo[1,5-a]p...)
Affinity DataIC50:  710nMAssay Description:Inhibition of CDK2/cyclin AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed