BDBM50334885 3-phenyl-5-(piperidin-3-yl)pyrazolo[1,5-a]pyrimidin-7-amine::CHEMBL1643243

SMILES Nc1cc(nc2c(cnn12)-c1ccccc1)C1CCCNC1

InChI Key InChIKey=PKMHWWNKFMBGBK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50334885   

TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50334885(3-phenyl-5-(piperidin-3-yl)pyrazolo[1,5-a]pyrimidi...)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of recombinant His-CHK1 expressed in baculovirus after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50334885(3-phenyl-5-(piperidin-3-yl)pyrazolo[1,5-a]pyrimidi...)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of CDK2/cyclin AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed