BDBM50334891 5-(piperidin-3-yl)-3-(thiophen-2-yl)pyrazolo[1,5-a]pyrimidin-7-amine::CHEMBL1643248

SMILES Nc1cc(nc2c(cnn12)-c1cccs1)C1CCCNC1

InChI Key InChIKey=WFRTXTYEVNAMFV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50334891   

TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50334891(5-(piperidin-3-yl)-3-(thiophen-2-yl)pyrazolo[1,5-a...)
Affinity DataIC50:  690nMAssay Description:Inhibition of CDK2/cyclin AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50334891(5-(piperidin-3-yl)-3-(thiophen-2-yl)pyrazolo[1,5-a...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of recombinant His-CHK1 expressed in baculovirus after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed