BDBM503349 6-amino-2-(4-aminoazepan-1-yl)-5- (2,3-dichlorophenyl)-pyrimidine-4- carboxamide::US11033547, Compound 49::US11696916, Compound 49
SMILES NC1CCCN(CC1)c1nc(N)c(c(n1)C(N)=O)-c1cccc(Cl)c1Cl
InChI Key InChIKey=SOVQPROKSCVFRZ-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 503349
Affinity DataIC50: 120nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair