BDBM50334914 3-((3-bromo-5-(2-fluorophenyl)pyrazolo[1,5-a]pyrimidin-7-ylamino)methyl)pyridine 1-oxide::CHEMBL1643465

SMILES [O-][n+]1cccc(CNc2cc(nc3c(Br)cnn23)-c2ccccc2F)c1

InChI Key InChIKey=FOIWJMGHUDACNX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50334914   

TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50334914(3-((3-bromo-5-(2-fluorophenyl)pyrazolo[1,5-a]pyrim...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of recombinant His-CHK1 expressed in baculovirus after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50334914(3-((3-bromo-5-(2-fluorophenyl)pyrazolo[1,5-a]pyrim...)
Affinity DataIC50:  13nMAssay Description:Inhibition of CDK2/cyclin AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed