BDBM50335495 4-(4-(thiiran-2-ylmethylsulfonyl)phenoxy)phenyl methanesulfonate::CHEMBL1651842::US10357546, JNMS-38

SMILES CS(=O)(=O)Oc1ccc(Oc2ccc(cc2)S(=O)(=O)CC2CS2)cc1

InChI Key InChIKey=IEHSRERHOYOHOA-UHFFFAOYSA-N

Data  16 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50335495   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335495(4-(4-(thiiran-2-ylmethylsulfonyl)phenoxy)phenyl me...)
Affinity DataKi:  5nMAssay Description:Inhibition of human recombinant MMP9 catalytic domain by substrate hydrolysis based fluorescence spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335495(4-(4-(thiiran-2-ylmethylsulfonyl)phenoxy)phenyl me...)
Affinity DataKi:  23nMAssay Description:Inhibition of MMP2 by substrate hydrolysis based fluorescence spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335495(4-(4-(thiiran-2-ylmethylsulfonyl)phenoxy)phenyl me...)
Affinity DataKi:  150nMAssay Description:Inhibition of human recombinant MMP14 catalytic domain by substrate hydrolysis based fluorescence spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335495(4-(4-(thiiran-2-ylmethylsulfonyl)phenoxy)phenyl me...)
Affinity DataKi:  600nMAssay Description:Inhibition of human recombinant MMP3 catalytic domain by substrate hydrolysis based fluorescence spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335495(4-(4-(thiiran-2-ylmethylsulfonyl)phenoxy)phenyl me...)
Affinity DataKi:  1.80E+4nMAssay Description:Inhibition of human recombinant MMP7 catalytic domain by substrate hydrolysis based fluorescence spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335495(4-(4-(thiiran-2-ylmethylsulfonyl)phenoxy)phenyl me...)
Affinity DataKi:  1.40E+5nMAssay Description:Inhibition of human recombinant MMP1 catalytic domain by substrate hydrolysis based fluorescence spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed