BDBM50335500 4-(Thiiran-2-ylmethylsulfonyl)phenyl ethanesulfonate::CHEMBL1651847

SMILES CCS(=O)(=O)Oc1ccc(cc1)S(=O)(=O)CC1CS1

InChI Key InChIKey=BXWKQAHPQICDHI-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50335500   

Target72 kDa type IV collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335500(4-(Thiiran-2-ylmethylsulfonyl)phenyl ethanesulfona...)
Affinity DataKi:  90nMAssay Description:Inhibition of MMP2 by substrate hydrolysis based fluorescence spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335500(4-(Thiiran-2-ylmethylsulfonyl)phenyl ethanesulfona...)
Affinity DataKi:  90nMAssay Description:Competitive inhibition of human MMP-2 assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335500(4-(Thiiran-2-ylmethylsulfonyl)phenyl ethanesulfona...)
Affinity DataKi:  1.10E+4nMAssay Description:Inhibition of human recombinant MMP14 catalytic domain by substrate hydrolysis based fluorescence spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))TBA
LigandPNGBDBM50335500(4-(Thiiran-2-ylmethylsulfonyl)phenyl ethanesulfona...)
Affinity DataKi:  1.20E+4nMAssay Description:Competitive inhibition of human MMP-9 assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))TBA
LigandPNGBDBM50335500(4-(Thiiran-2-ylmethylsulfonyl)phenyl ethanesulfona...)
Affinity DataKi:  1.20E+4nMAssay Description:Inhibition of human recombinant MMP9 catalytic domain by substrate hydrolysis based fluorescence spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335500(4-(Thiiran-2-ylmethylsulfonyl)phenyl ethanesulfona...)
Affinity DataKi:  2.60E+4nMAssay Description:Inhibition of human recombinant MMP7 catalytic domain by substrate hydrolysis based fluorescence spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed