BDBM50335669 (3R,4S)-ethyl 4-(2-(5-fluoro-2-hydroxyphenyl)quinazolin-4-ylamino)pyrrolidine-3-carboxylate::CHEMBL1650055

SMILES CCOC(=O)[C@@H]1CNC[C@H]1Nc1nc(nc2ccccc12)-c1cc(F)ccc1O

InChI Key InChIKey=FMLDBFUXSBWTPY-NVXWUHKLSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50335669   

TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50335669((3R,4S)-ethyl 4-(2-(5-fluoro-2-hydroxyphenyl)quina...)
Affinity DataIC50:  154nMAssay Description:Inhibition of CHK2 by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50335669((3R,4S)-ethyl 4-(2-(5-fluoro-2-hydroxyphenyl)quina...)
Affinity DataIC50:  2.80E+4nMAssay Description:Inhibition of CHK1 by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed