BDBM50335671 4-fluoro-2-(4-((3S,4R)-4-(2-hydroxypropan-2-yl)pyrrolidin-3-ylamino)quinazolin-2-yl)phenol::CHEMBL1650117

SMILES CC(C)(O)[C@@H]1CNC[C@H]1Nc1nc(nc2ccccc12)-c1cc(F)ccc1O

InChI Key InChIKey=CEIIDGPSFYGDIQ-NVXWUHKLSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50335671   

TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50335671(4-fluoro-2-(4-((3S,4R)-4-(2-hydroxypropan-2-yl)pyr...)
Affinity DataIC50:  21nMAssay Description:Inhibition of CHK2 by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50335671(4-fluoro-2-(4-((3S,4R)-4-(2-hydroxypropan-2-yl)pyr...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of CHK1 by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed