BDBM50335677 (S)-2-(7-(3-hydroxypropyl)-4-(pyrrolidin-3-ylamino)quinazolin-2-yl)phenol::CHEMBL1650122

SMILES OCCCc1ccc2c(N[C@H]3CCNC3)nc(nc2c1)-c1ccccc1O

InChI Key InChIKey=MXLJGGDSSLTJIR-HNNXBMFYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50335677   

TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50335677((S)-2-(7-(3-hydroxypropyl)-4-(pyrrolidin-3-ylamino...)
Affinity DataIC50:  78nMAssay Description:Inhibition of CHK2 by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50335677((S)-2-(7-(3-hydroxypropyl)-4-(pyrrolidin-3-ylamino...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of CHK1 by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed